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Honeymoon in Shimla is very popular with couples from all over the world. Besides Shimla, other hill-stations popular with tourist include Manali, Dalhousie, Dharamshala, Chamba, Khajjiar, Kasauli and Kullu.
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Sion Partial Remission 11 (25) Stable Disease 12 (27) Progressive Disease 21 (48) Not assessable 0 (0) Survival (Months) Time to Progression 3.6 Overall Survival 10.0 (0) 9 (60) 5 (33) 1 (7) 0 (0)0 (0) 2 (9) 8 (32) 13 (59) 0 (0)0 (0) 0.002 10 (36) 10 (36) 0.001 8 (30) 0 (0)0 (0) 1 (6) 2 (13) 13 (81) 0 (0) 0.03 10.3.1 10.0.Only statistically significant p values have been included
Oscience. Trends Neurosci. 1999;22(4):167-173. PubMed Silverman ES, Collins T. Pathways of Egr-1-mediated gene transcription in vascular biology. Am J Pathol. 1999;154(3):665-70. doi:10.1016/S00029440(10)65312-6. PubMed PMID: 10079243; PMCID: PMC1866415. Thiel G, Cibelli G. Regulation of life and death by the zinc finger transcription factor Egr-1. J Cell Physiol. 2002;193(3):287-292. doi:10.1002
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Esults in an increased sensitivity to TGF-beta signaling. BMC Cancer. 2011;11:59. PubMed. 31. Imamichi Y, Waidmann O, Hein R, Eleftheriou P, Giehl K, Menke A. TGF betainduced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4. Biol Chem. 2005;386(3):225-236. PubMed. 32. Gauger KJ, Shimono A, Crisi GM, Schneider SS. Loss of SFRP
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Poprotein; SFRP1: Secreted frizzled-related protein-1; TAM: Tumor Associated Macrophage; TGF-: Transforming growth factor- Acknowledgements Not applicable.5.6.7. Funding The design of this study, collection, analysis, interpretation, and writing of the manuscript were made possible because of the funding support by the Rays of Hope Foundation. Availability of data and materials The raw files are
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